Abstract: AIM To analyze the feasibility and success rate of modified balloon crushing technique with transradial access in patients with bifurcation lesions. METHODS Seventeen cases of patients with coronary angiography/transradial approach confirmed bifurcation lesions （branch diameter>2.5 mm and the degree of bifurcation stenosis>70%） were enrolled in the study. Bifurcation lesions were treated with modified balloon crushing with transradial access. RESULTS Rapamycin stents were successfully implanted in all bifurcation lesions and final kissing balloon inflation was performed in 15 bifurcated lesions. Angiography showed that the blood flow was TIMI Ⅲ and no serious complications such as acute side-branch occlusion, stent thrombosis, cardiogenic shock or death happened after the modified balloon crushing. CONCLUSION Modified balloon crushing technique can be performed safely with low rate of restenosis. Good results can be achieved if final kissing balloon inflation is performed.