急性心肌梗死后择期冠脉介入治疗对左室重构和心功能的影响

    Effects of delayed percutaneous coronary interventions on left ventricular remodeling and cardiac function after acute myocardial infarction

    • 摘要: 目的 探讨急性心肌梗死(AMI)后择期经皮冠状动脉介入(PCI)治疗对左心室重构和心功能的影响。方法 112例AMI患者,分为PCI组和药物治疗组,PCI组于发病后1~2周内行PCI治疗,所有患者于发病后1~2周时、4周和24周时行超声心动图(UCG)检查,观察左心室收缩末容积指数(LVESVI)、左心室舒张末容积指数(LVEDVI)和左室射血分数(LVEF)。结果 行PCI治疗后,血管再通率为100%,术后4周和24周的LVESVI、LVEDVI和LVEF均明显优于术前,与药物治疗组比较有显著性差异(P<0.05)。结论 AMI后择期PCI治疗能够有效抑制左心室重构,改善心功能。

       

      Abstract: AIM To study the effects of delayed percutaneous coronary interventions(PCI) on left ventricular remodeling and cardiac function after acute myocardial infarction(AMI).METHODS The 112 cases with acute myocardial infarction were treated with medicine and with delayed PCI one or two weeks after infarction.The echocardiography was applied to observe the alternation of left ventricular endsystolic volume index(LVESVI),left ventricular enddiastolic volume index(LVEDVI) and left ventricular ejection fraction(LVEF) with the total cases during two weeks and four weeks and twentyfour weeks. RESULTS In patients treated with PCI,reperfusion rate were 100%.The improvements of LVESVI and LVEDVI and LVEF were significant after PCI,patients who underwent PCI had lower mortality rate than those who were treated with medicine(P<0.05).CONCLUSION Delayed PCI can still inhibits left ventricular remodeling and improve cardiac function.

       

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