主动脉瓣钙化与冠心病有关联

龚东; 楼建英; 彭健; 张伟; 王达理; 钱维源

主动脉瓣钙化与冠心病有关联

Association between aortic valve calcification and coronary artery disease

摘要

摘要: 目的: 探讨中国南方部分汉族人群主动脉瓣钙化与冠心病之间的关系。方法：选取同期行冠状动脉造影检查和超声心动图检查患者1 153例，探讨主动脉瓣钙化与冠心病的相关性。结果：冠心病组主动脉瓣钙化的检出率明显高于非冠心病组（32.6% vs. 13.9%,P<0.01），多因素Logistic回归分析结果显示，除传统危险因素如年龄、性别、高脂血症、糖尿病外，主动脉瓣钙化也是全组冠心病的一项独立的预测因子(OR=1.53，P<0.05)。结论：主动脉瓣钙化与全组冠心病发病之间存在显著的相关性，是冠心病的一项有意义的独立预测因子。

Abstract: AIM: To determine the relationship between aortic valve calcification (AVC) and coronary artery disease (CAD) in part of the Han population in southern China. METHODS: Enrolled in the study were 1 153 subjects who underwent both transthoracic echocardiography (TTE) and coronary arteriography (CAG), and the relationship between aortic valve calcification (AVC) and CAD was explored. RESULTS: The prevalence of AVC was significantly higher in the CAD group compared with that in non-CAD group (32.6% vs. 13.9%, P<0.01). Multiple logistic regression analysis showed that in addition to age, gender, diabetes mellitus and hyperlipidemia (all P<0.01), AVC (P<0.05) was an independent positive predictor of coronary arteriography. CONCLUSION: There is a significant association between the presence of AVC and CAD. Aortic valve calcification is an independent predictor of CAD.

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