阻塞性睡眠呼吸暂停综合征与左房增大的关联性

Association of obstructive sleep apnea syndrome and left atrial enlargement

摘要: 目的心脏的重构与阻塞性睡眠呼吸暂停综合征（obtructive sleep apnea syndrome，OSAS）患者心血管疾病的发生发展有着密切的关系, 本文探讨OSAS与左房增大的关系。方法所有病例予睡眠多导图监测（PSG）、超声心动图检查以及血生化等检测，据PSG分为单纯鼾症组（n=41）和OSAS组（n=46），对两组的各个相关因素进行比较,筛选出有意义的变量后再予多因素Logistic回归分析。结果 OSAS组的左房内径（LAD）显著大于单纯鼾症组，有统计学差异（P<0.01）。结论左房增大是OSAS的独立相关因素。

Abstract: AIM To study the relationship between obstructive sleep apnea syndrome (OSAS) and left atrial enlargement in patients. METHODS All participants underwent polysomnography (PSG), echocardiography and blood biochemical detection. According to PSG, participants were divided into snoring group (n=41) and OSAS group (n=46). Relevant factors were compared and multiple logistic regression was performed on the variables with significant statistical difference. RESULTS Left atrial diameter (LAD) in OSAS group was higher than that in the snoring group (P<0.01). CONCLUSION The findings of this study show that the severity of OSAS is independently associated with left atrial enlargement.