任春霖, 陈志勇, 胡胜利. 高血压病患者脉搏波传导速度与动态血压各指标的相关性分析[J]. 心脏杂志, 2010, 22(6): 874-877.
    引用本文: 任春霖, 陈志勇, 胡胜利. 高血压病患者脉搏波传导速度与动态血压各指标的相关性分析[J]. 心脏杂志, 2010, 22(6): 874-877.
    Analysis of correlation between pulse wave velocity and indexes of ambulatory blood pressure in hypertensive patients[J]. Chinese Heart Journal, 2010, 22(6): 874-877.
    Citation: Analysis of correlation between pulse wave velocity and indexes of ambulatory blood pressure in hypertensive patients[J]. Chinese Heart Journal, 2010, 22(6): 874-877.

    高血压病患者脉搏波传导速度与动态血压各指标的相关性分析

    Analysis of correlation between pulse wave velocity and indexes of ambulatory blood pressure in hypertensive patients

    • 摘要: 目的: 探讨高血压病患者脉搏波传导速度(PWV)与动态血压(ABPM)各指标的相关性。方法: 对200例高血压病患者按年龄分为非老年高血压患者(年龄<60岁)和老年高血压患者(年龄≥60岁)两组;每组中再按PWV正常值分为<9 m/s和≥9 m/s两组。收集相关临床资料,测量身高、体质量、腰围、臀围,检测PWV和ABPM,计算24 h平均脉压(PP)、脉压指数(PPI)、体质量指数(BMI)、腰臀比(WHR),分析ABPM的各值及其他有关因素与PWV的相关性。结果: 与非老年高血压病患者比较:老年高血压病患者WHR、PP、PPI、PWV显著升高(P<0.05,P<0.01);这两组中PWV≥9 m/s的患者,SBP、DBP、PP、PPI均高于同组内PWV<9 m/s的患者,组内比较有显著差异性(P<0.05,P<0.01);经Pearson相关分析:PPI与 PWV 相关系数r值(0.501)大于SBP、DBP、PP的r值(0.398、-0.251、0.418)。结论: 高血压病患者PPI与PWV密切相关,在反映大动脉硬化程度上PPI优于动态血压其他指标。

       

      Abstract: AIM: To explore the correlation between pulse wave velocity (PWV) and indexes of ambulatory blood pressure (ABPM) in patients with hypertension. METHODS: A total of 200 patients with hypertension were divided into two groups: nonelderly (<60 years) group and elderly (≥60 years) group. In both groups, patients were subdivided into two groups: PWV<9 m/sec group and PWV≥9 m/sec group. Clinical data, PWV and indexes of ABPM were collected and the correlation between the indexes of ABPM, other relevant factors and PWV was analyzed. RESULTS: Compared with those in the nonelderly group, waist/hip ratio, pulse pressure (PP), pulse pressure index (PPI) and PWV in the elderly group were significantly higher (P<0.05 or P<0.01). Systolic blood pressure (SBP), diastolic blood pressure (DBP), PP and PPI of patients in PWV≥9 m/sec group were significantly higher than those in PWV <9 m/sec group in the same group (P<0.05 or P<0.01). Pearson correlation analysis showed that PPI was more closely correlated with PWV than with body mass index (BMI), PPI, PP, SBP and DBP. CONCLUSION: PWV is correlated with PP, SBP and DBP and significantly correlated with PPI in patients with hypertension.

       

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