Abstract: AIM To assess the association between consumption of Chinese prickly ash and right coronary artery stenosis. METHODS Patients who underwent coronary angiongraphy from September 2013 to October 2014 in our hospital were investigated. Consumption of Chinese prickly ash was assessed and multiple linear regression model was used to analyze the association between consumption of Chinese prickly ash and right coronary artery stenosis. RESULTS One hundred and eighty-seven patients were included in this study. Single factor analysis found a significant difference between the frequency of different consumption patterns of Chinese prickly ash and different degrees of right coronary artery stenosis (P<0.01). Multiple linear regression model showed that consumption of Chinese prickly ash was associated with right coronary artery stenosis (P<0.01, 95%CI: -39.152, -22.790). Spearman's correlation analysis showed a negative correlation between Chinese prickly ash and right coronary artery stenosis (r=-0.59, P<0.01). CONCLUSION Consumption of Chinese prickly ash may be closely associated with right coronary stenosis.