左心室射血分数保留的心力衰竭诊治的研究进展

Review of progression in diagnosis and treatment of heart failure with preserved ejection fraction

摘要: 左心室射血分数(LVEF)保留的心力衰竭（HFPEF）旧称舒张功能不全的心力衰竭或收缩功能正常的心力衰竭，是一种日益流行的健康问题，相对与LVEF降低的心力衰竭（HFREF）而言，其特征是LVEF正常或接近正常，但有心力衰竭的临床表现。2013 ACCF/AHA心力衰竭管理指南［1］大大提高了对HFPEF的重视程度，将LVEF≥50%定义为 HFPEF。临床上该型患者的发病率逐渐增长，且预后比HFREF更差［2］，然而目前尚无明确的诊断标准和治疗方法。本文旨在对HFPEF目前的研究进展进行综述。

Abstract: Heart failure with preserved ejection fraction (HFPEF), formerly known as diastolic heart failure or heart failure with normal systolic function, is an increasing health problem. It is characterized by a normal or nearly normal left ventricular ejection fraction compared with HFREF, but with clinical manifestations of heart failure. The 2013 ACCF/AHA Guideline for the Management of Heart Failure has greatly improved the degree of attention to HFPEF. If left ventricular ejection fraction (LVEF) is ≥50%, it is defined as HFPEF. The incidence of this type increases gradually, and prognosis is poorer than for HFREF. However, there are no definite diagnostic standard and treatment methods. This paper mainly summarizes recent research of HFPEF.