心磁图和心电图早期诊断冠心病的真实性指标比较

Contrast study of sensitivity and specificity between magnetocardiography and electrocardiogram in early diagnosis of coronary artery disease in patients with acute chest pain

摘要: 目的比较心磁图（MCG）和心电图(ECG)对急性胸痛患者早期诊断冠心病的敏感度和特异度。方法入选287例急性胸痛患者，先后给患者做MCG和ECG，然后均接受冠状动脉造影(CAG)检查。以CAG为标准诊断方法(金标准),比较MCG和ECG诊断冠心病的灵敏度和特异度。结果 MCG诊断冠心病的灵敏度和特异度分别为88.9%和73.2%，ECG诊断冠心病的灵敏度和特异度为53.2%和55.7%。结论在急性胸痛患者早期诊断过程中,MCG诊断的灵敏度和特异度均显著高于ECG。

Abstract: AIM To investigate the sensitivity of magnetocardiography (MCG) and electrocardiogram (ECG) for the early diagnosis of coronary artery disease (CAD) in patients with acute chest pain. METHODS Two hundred and eighty seven patients with acute chest pain were selected. MCG recordings and ECG data of these patients were obtained and ventricular repolarization measurements including QRS-, R-, T-wave and ST-T period were compared between MCG and ECG. All patients underwent coronary angiogram and patients with coronary artery narrowing ≥70% in at least 1-vessel were defined as CAD. RESULTS The sensitivity and specificity of MCG and ECG in diagnosing CAD were 86.7% and 77.2% vs. 70.1% and 37.7%. CONCLUSION MCG has higher sensitivity and specificity than ECG. Thus, MCG is of potential clinical application in early diagnosis of CAD in patients with chest pain.