扩张性心肌病患者左室射血分数与胆固醇水平的相关性

Correlation between left ventricular ejection fraction and total cholesterol in dilated cardiomyopathy

摘要: 目的目的分析扩张性心肌病（DCM）患者左室射血分数(LVEF)与血清总胆固醇（TC）的关系。方法选取住院DCM患者123例，分为LVEF>40％组（34例）和 LVEF≤40％组（89例）。入院后收集患者一般情况及测定血液生化，以超声心动图检查患者的心脏功能及结构，并进行比较。结果 LVEF>40%组与LVEF≤40%患者比较：LVEF>40%组年龄小于LVEF≤40%组(P<0.05)；LVEF>40%组TC显著高于LVEF≤40%组(P<0.05)。TC与LVEF呈正相关（r=0.287,P<0.01）。结论 DCM患者LVEF与TC有相关性。

Abstract: AIM To investigate the correlation between left ventricular ejection fraction and serum total cholesterol in patients with dilated cardiomyopathy (DCM) and to provide an index for the emergence of heart failure. METHODSOne hundred and twenty-three patients with dilated cardiomyopathy were divided into two groups: LVEF >40% group (n=34) and LVEF ≤40% group (n=89). General information and biochemical data of serum were collected, and the cardiac structure and functions were determined by echocardiogram and compared. RESULTSPatients in the LVEF>40% group were younger than LVEF≤40% group (P<0.05). Total cholesterol in LVEF>40% group was significantly higher than in LVEF≤40% group (P<0.05). Total cholesterol was positively related to LVEF (r=0.287, P<0.01). CONCLUSIONTotal cholesterol may serve as a helpful predictor of heart failure.