联合踝臂指数和钙化积分判定老年冠脉3支病变的价值

Combination of ankle-brachial index and coronary artery calcium score as a predictor for 3-vessel coronary artery disease

摘要: 目的探讨联合应用踝臂指数（ankle-brachial index,ABI）和钙化积分(coronary artery calcium score,CACS)提高判定冠状动脉3支病变的价值。方法选择连续96例行冠脉造影的老年患者，分别予ABI检测和64排CT检测CACS。结果 ABI<0.9、CACS>400判定冠脉3支病变敏感度分别为58％、64％，特异度分别为87％、86％，联合使用敏感度显著提高（85％），特异度未明显降低（83％）。结论 ABI<0.9、CACS>400一定程度上能够判定老年人冠脉3支病变，联合使用判定价值更大。

Abstract: AIM To discuss the predictive value of the combination of ankle-brachial index(ABI) and coronary artery calcium score（CACS）for 3-vessel coronary artery disease (CAD). METHODS This study enrolled 96 patients, who underwent ABI measurement and 64-channel multidetector CT , for their CACS before coronary angiography. RESULTS The respective sensitivities of ABI and CACS for 3-vesssel CAD were 58% and 64%, and the specificities were 87.3％ and 85%. After combining the two methods, the sensitivity was notably improved to 85%, but the specificity was decreased to 82%. CONCLUSION ABI<0.9 and CACS>400 can be used to predict 3-vessel CAD, but the predictive value is notably improved after the combination of ABI<0.9 and CACS>400.