Abstract: AIM:To explore the clinical characteristics in patients who died due to inhospital chronic heart failure (HF). METHODS: Clinical data of 1 472 patients with chronic HF were retrospectively analyzed. The patients were divided into two groups: 131 cases for the inhospital group who died and 1 341 cases in the survival group. Clinical data of the two groups were analyzed and compared. RESULTS: Total mortality in the 1 472 patients with chronic HF was 89% (131/1 472). Age, blood sugar, blood pressure, cholesterol, heart cavity diameter and ejection fraction in the inhospital group of patients who died were significantly higher than those in the survival group. The complication rate and multiple risk factors were also higher in the inhospital patient group who died. CONCLUSION: Advanced age, hypertension, hyperglycemia and hyperlipemia all increase the mortality of patients with chronic HF. Higher risk factors represent higher mortality rate in chronic HF patients.