Abstract: AIM To compare the clinical characteristics of dialysis and nondialysis patients with acute myocardial infarction. METHODS Retrospective analysis of the clinical characteristics of 185 chronic kideny disease patients with acute myocardial infarction was conducted. RESULTS Compared with the nondialysis patients, fewer dialysis patients were diagnosed as having myocardial infarction on admission and chest pain and ST elevation presented in fewer dialysis patients. Troponin was positive in more dialysis patients, LVEF was lower than nondialysis patients, and in-hospital death was much higher. CONCLUSION Dialysis patients hospitalized for AMI have poor outcomes and their mortality rate is higher.