匡荣仁, 徐 燕, 洪 雷, 梁华生, 方胜先. 稳心颗粒对心房颤动患者射频消融术后早期复发的影响[J]. 心脏杂志, 2016, 28(5): 546-548.
    引用本文: 匡荣仁, 徐 燕, 洪 雷, 梁华生, 方胜先. 稳心颗粒对心房颤动患者射频消融术后早期复发的影响[J]. 心脏杂志, 2016, 28(5): 546-548.
    shu
    Effect of wenxin granule on early recurrence after radiofrequency ablation in patients with atrial fibrillation[J]. Chinese Heart Journal, 2016, 28(5): 546-548.
    Citation: Effect of wenxin granule on early recurrence after radiofrequency ablation in patients with atrial fibrillation[J]. Chinese Heart Journal, 2016, 28(5): 546-548.
    shu

    稳心颗粒对心房颤动患者射频消融术后早期复发的影响

    Effect of wenxin granule on early recurrence after radiofrequency ablation in patients with atrial fibrillation

      摘要
    • 摘要: 目的 观察稳心颗粒对心房颤动患者射频消融术后早期复发的影响。 方法 入选拟行房颤射频消融术的住院患者，其中试药组 35例（稳心颗粒组）和对照组 36例。患者射频消融术后常规给予胺碘酮和华法林，试药组加用稳心颗粒。观察两者入院时及术后3个月血清氨基末端B型钠尿肽原（NT-proBNP）水平、入院时及术后3个月左房内径大小及早期复发情况。结果 试药组早期复发率为9%，对照组早期复发率为31%，两组比较差别有显著意义（P<0.05）；术后3个月两组NT-proBNP水平及左房内径呈下降趋势，且试药组明显低于对照组(P<0.05)。结论 稳心颗粒能够减少房颤射频术后早期复发，降低NT-proBNP水平及缩小左房内径。

       

      Abstract: AIM To discuss the effect of wenxin granule on early recurrence after radiofrequency ablation (RFCA) in patients with atrial fibrillation (AF). METHODSPersistent AF patients were randomized into wenxin granule group (n=35) and control group (n=36). The rate of AF early recurrence, NT-proBNP and left atrial diameter were observed before and 3 months after RFCA. RESULTSThe rate of AF early recurrence in wenxin granule group was significantly lower than in control group (8.6% vs. 30.6%; P<0.05). NT-proBNP and left atrial diameter in wenxin granule group were significantly lower than those in the control group 3 months after RFCA (P<0.05). CONCLUSIONWenxin granule can significantly lower the rate of AF early recurrence after RFCA and reduce NT-proBNP and left atrial diameter in patients with AF.

       

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