Abstract: AIM To evaluate our experience of mitral valve repair in combination with left ventricular restoration and coronary artery bypass graft(CABG) for post-infarction ventricular aneurysm and mitral regurgitation so as to improve the clinical results for these patients. METHODS From January 2001 to December 2008, 32 consecutive patients with left ventricular aneurysm and ischemic mitral valve regurgitation underwent mitral valve repair combined with ventriculoplasty and CABG. Clinical findings were reviewed retrospectively and the duration of follow-up was 46-175 months. RESULTS Operative mortality was 3%. One-year and 5-year survival rates were, respectively, 97% and 74%. During follow-up, three patients(9%) had NYHA class Ⅲ and IV and three patients(9%) had ≥ 2+ mitral regurgitation. The surgical technique for ventriculoplasty and the approach for mitral valve repair did not significantly affect the clinical outcomes. CONCLUSION Combined mitral and left ventricular reconstruction and coronary revascularization is effective for ischemic left ventricular aneurysm with mitral regurgitation. Short- and long-term clinical outcomes are satisfactory.