Abstract: AIM: To evaluate the efficacy of standardized chronic disease management in outpatients with coronary heart disease in terms of drug compliance,cardiovascular events,readmission rate and rating of cardiac function. METHODS: One hundred and eighty patients with coronary heart disease were divided into standardized chronic disease management group and control group. The standardized chronic disease management group was followed up regularly and regular examination was conducted every 3 months,whereas the control group was followed up by telephone or clinic visit every month. Drug compliance,cardiovascular readmission rate,and heart function grading( NYHA grading) were observed. RESULTS: A2-year follow-up showed that the percentage of taking aspirin and clopidogrel( 74 vs. 54%,P < 0. 01),statins( 69 vs. 46%,P <0. 01),ACEI/ARB( 76 vs. 46%,P <0. 01) and beta blockers( 42 vs. 63%,P <0. 05) in standardized chronic disease management group were higher than those in the control group. Readmission rate of cardiovascular events in standardized chronic disease management group was also lower( 26 vs. 42%,P <0. 05) and the cardiac function class was better than those in control group. CONCLUSION: Standardized chronic disease management for patients with coronary heart disease improves drug compliance and reduces cardiovascular readmission rate.