Abstract:
AIM To study the relationship between different pretreatment methods and clinical prognosis of patients with coronary artery disease treated with drug-coated balloon (DCB).
METHODS The study prospectively included 2 027 patients with single target lesions who underwent percutaneous coronary intervention (PCI) and received DCB alone in our hospital from December 1, 2015 to December 1, 2019. Among the 2 027 patients, only semi-compliant or high-pressure balloon preconditioning was used as the control group, and 1413 patients with cutting or spinous process balloon preconditioning were used as the observation group. The main end events were 36-month vascular-related composite end points, and the secondary end events were cardiogenic death, target vessel myocardial infarction and target vessel revascularization.
RESULTS There was no significant difference in baseline data between the two groups of patients. The age and prevalence of diabetes in the control group were higher than those in the observation group (P<0.05). The control group had a higher proportion of convoluted branches (P<0.05), while the observation group had a higher proportion of anterior descending branches (P<0.05). The 36 month follow-up showed that the incidence of vascular related composite endpoint, cardiac death, target vessel myocardial infarction and target vessel revascularization events in the observation group was significantly lower than that in the control group.
CONCLUSION For patients with coronary heart disease treated only with DCB, the 36-month follow-up showed that cutting balloon combined with DCB was safe and effective in the treatment of coronary artery disease, accompanied by lower vascular-related composite endpoints.
下载: