杨丽, 赵帅, 朱伯达, 陈焱, 禹天同, 刘浩林, 韩鹏, 马炳琦, 王嘉仪, 魏志宏, 高好考, 李成祥, 廉坤. 经皮冠状动脉介入术对慢性完全闭塞病变合并左心室射血分数降低冠心病患者的疗效[J]. 心脏杂志, 2024, 36(1): 34-39. DOI: 10.12125/j.chj.202306052
    引用本文: 杨丽, 赵帅, 朱伯达, 陈焱, 禹天同, 刘浩林, 韩鹏, 马炳琦, 王嘉仪, 魏志宏, 高好考, 李成祥, 廉坤. 经皮冠状动脉介入术对慢性完全闭塞病变合并左心室射血分数降低冠心病患者的疗效[J]. 心脏杂志, 2024, 36(1): 34-39. DOI: 10.12125/j.chj.202306052
    shu
    YANG Li, ZHAO Shuai, ZHU Bo-da, CHEN Yan, YU Tian-tong, LIU Hao-lin, HAN Peng, MA Bing-qi, Wang Jia-yi, WEI Zhi-hong, GAO Hao-kao, LI Cheng-xiang, LIAN Kun. Successful percutaneous coronary intervention improves symptoms in chronic total occlusion patients with low left ventricular ejection fraction[J]. Chinese Heart Journal, 2024, 36(1): 34-39. DOI: 10.12125/j.chj.202306052
    Citation: YANG Li, ZHAO Shuai, ZHU Bo-da, CHEN Yan, YU Tian-tong, LIU Hao-lin, HAN Peng, MA Bing-qi, Wang Jia-yi, WEI Zhi-hong, GAO Hao-kao, LI Cheng-xiang, LIAN Kun. Successful percutaneous coronary intervention improves symptoms in chronic total occlusion patients with low left ventricular ejection fraction[J]. Chinese Heart Journal, 2024, 36(1): 34-39. DOI: 10.12125/j.chj.202306052
    shu

    经皮冠状动脉介入术对慢性完全闭塞病变合并左心室射血分数降低冠心病患者的疗效

    Successful percutaneous coronary intervention improves symptoms in chronic total occlusion patients with low left ventricular ejection fraction

      摘要
    • 摘要:
      目的 评估成功的经皮冠状动脉介入术（PCI）能否改善慢性完全闭塞病变（chronic total occlusion, CTO）合并左心室射血分数（LVEF）降低的冠心病患者症状。
      方法 连续性纳入2018年4月～2021年5月在空军军医大学第一附属医院接受PCI的CTO患者，并将其分为3组：LVEF ≥ 50%组、50%>LVEF>35%组和LVEF ≤ 35%组。收集患者术前基线资料，分别采用Rose呼吸困难量表（Rose dyspnea scale , RDS）和西雅图心绞痛问卷（Seattle angina questionnaire, SAQ）评估患者呼吸困难和心绞痛症状，收集手术资料，分别于1月和1年后对患者进行随访。
      结果 共成功纳入1076例接受PCI的CTO患者，LVEF ≤ 35%的患者有114例（10.6%），其既往心肌梗死病史较多，NYHA心功能III/IV级、多支血管病变和多支CTO病变的比例较高（P<0.01）。术后1月和1年随访时，CTO合并LVEF ≤ 35%的患者呼吸困难和心绞痛症状均有明显改善（P<0.01），且其改善程度与其他两组相似。
      结论 成功PCI显著改善CTO合并LVEF降低的冠心病患者呼吸困难和心绞痛症状。

       

      Abstract:
      AIM To assess whether successful percutaneous coronary intervention (PCI) could improve symptoms in chronic total occlusion (CTO) patients with low left ventricular ejection fraction (LVEF, ≤35%).
      METHODS CTO patients who underwent PCI from April 2018 to May 2021 were prospectively and consecutively enrolled and they were subdivided into 3 groups: LVEF ≥ 50%, 50%>LVEF>35%, and LVEF ≤ 35%. Detailed baseline characteristics and symptoms including dyspnea and angina were assessed respectively with the Rose dyspnea scale (RDS) and Seattle angina questionnaire (SAQ). Procedural details as well as 1 month and 1 year follow-up data were collected.
      RESULTS Of the 1076CTO patients, LVEF ≤ 35% was present in 114 patients (10.6%), who had more previous myocardial infarction and higher proportion of NYHA functional class III/IV, multivessel disease and multi-CTO lesion (P<0.01). At 1 month and 1 year follow-up, dyspnea and angina were markedly relieved regardless of LVEF (P<0.01), notably at a similar degree between patients with LVEF ≤ 35% and the other two groups.
      CONCLUSION Successful PCI can significantly relieve dyspnea and angina in CTO patients with low LVEF.

       

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