AIM  To study the clinical features and long-term prognosis of over-aged patients undergoing percutaneous coronary intervention (PCI) and to discuss the risk factors for the prognosis.

  METHODS  Included for this study were 397 patients who underwent PCI over one year and received coronary angiography during the admission. The patients were divided by age into over-aged group (≥80 years) and control group (<80 years). Clinical characteristics and echocardiographic data were examined and long-term clinical follow-up was carried out to investigate the rates of adverse events. Logistic regression analysis was performed to analyzed the risk factors for the prognosis.

  RESULTS  The average age of patients in the super elderly group was (83 ± 3) years, which was significantly higher than that in the control group (63 ± 9) (P<0.01). The late in stent restenosis rate was 40% in the super elderly group and 32% in the control group. There was no significant difference between the two groups. Compared with the control group, the levels of leukocyte (P<0.05), hemoglobin (P<0.01), total triiodothyronine (T3) (P<0.01) and free T3 (P<0.01) in the super elderly group were lower; The levels of hypertension (P<0.05) and serum creatinine (P<0.01) were higher; Compared with the results of echocardiography in the control group, the thickness of ventricular septum in the super elderly group was larger and the left ventricular end diastolic diameter was smaller, the difference was statistically significant (P<0.05). There was no significant difference in ejection fraction between the two groups. There was no significant difference in the incidence of adverse events between the two groups (P<0.01); Age is an independent risk factor for the prognosis of PCI patients.

  CONCLUSION  Over-aged patients undergoing PCI might have higher rates of hypertension, renal dysfunction and thyroid dysfunction. The long-term prognosis is poorer. Age is the independent risk factor for the adverse prognosis.