干琴静, 杨凌锋, 邱原刚. 心房颤动合并肺动脉高压的临床特征与危险因素[J]. 心脏杂志, 2021, 33(5): 514-517. DOI: 10.12125/j.chj.202101089
    引用本文: 干琴静, 杨凌锋, 邱原刚. 心房颤动合并肺动脉高压的临床特征与危险因素[J]. 心脏杂志, 2021, 33(5): 514-517. DOI: 10.12125/j.chj.202101089
    shu
    Qin-jing GAN, Ling-feng YANG, Yuan-gang QIU. Clinical characteristics and risk factors of atrial fibrillation with pulmonary arterial hypertension[J]. Chinese Heart Journal, 2021, 33(5): 514-517. DOI: 10.12125/j.chj.202101089
    Citation: Qin-jing GAN, Ling-feng YANG, Yuan-gang QIU. Clinical characteristics and risk factors of atrial fibrillation with pulmonary arterial hypertension[J]. Chinese Heart Journal, 2021, 33(5): 514-517. DOI: 10.12125/j.chj.202101089
    shu

    心房颤动合并肺动脉高压的临床特征与危险因素

    Clinical characteristics and risk factors of atrial fibrillation with pulmonary arterial hypertension

      摘要
    • 摘要:
        目的  探讨肺动脉高压（pulmonary arterial hypertension, PAH）在心房颤动（atrial fibrillation，AF）患者中的临床特征与危险因素。
        方法  纳入于2016年11月～2019年11月连续入院的292名确诊AF的患者，根据临床分类分为两组：①阵发性AF组167例（发作后在7天内能自行或干预终止的AF）；②非阵发性AF组125例（持续时间超过7天的AF）。以超声心动图为主要诊断标准，PAH采用三尖瓣反流法估算的肺动脉压值进行诊断。收集患者的临床信息进行统计分析。
        结果  对292例AF患者进行分析：阵发性AF患者167例，非阵发性AF125例，分别检出PAH100例（占59.9%）和111例（占88.9%），非阵发性AF合并PAH比率高(P<0.01）；与阵发性AF组比较，非阵发性AF组年龄大，肺动脉压数值高（均P<0.01）。单因素分析结果发现年龄>65岁、起搏器置入术后、D-二聚体升高（前3项均P<0.05）、非阵发性AF、左房直径、右房扩大以及左室射血分数（LVEF）（后4项均P<0.01）与PAH显著相关。多因素分析发现右房扩大（P<0.01）、非阵发性AF和LVEF（均P<0.05）是AF合并PAH的独立危险因素。
        结论  非阵发性AF并发PAH比率较高，非阵发性AF、右房扩大、左室EF值均为AF合并PAH的独立危险因素。

       

      Abstract:
        AIM   To analyze the prevalence of pulmonary arterial hypertension (PAH) in patients with atrial fibrillation (AF) and the risk factors and the clinical characteristics of atrial fibrillation with pulmonary arterial hypertension.
        METHODS  A total of 292 patients with AF from November 2016 to November 2019 were recruited in this study. The patients were divided into two groups: paroxysmal AF group (n = 167) and non-paroxysmal AF group (n = 125). With echocardiography as the main diagnostic criteria, pulmonary hypertension was diagnosed by tricuspid regurgitation. Clinical data of the patients were collected for statistical analysis.
        RESULTS  Among the 292 patients, PAH was found in 100 patients (59.9%) in paroxysmal AF group and in 111 patients (88.9%) in non-paroxysmal AF group. Univariate analysis and multivariate logistic regression analysis showed that non-paroxysmal atrial fibrillation (P<0.05), right atrial enlargement (OR = 6.641, 95%CI 2.397~18.402, P<0.01) and left ventricular ejection fraction (P<0.01) were independent risk factors for atrial fibrillation with pulmonary arterial hypertension.
        CONCLUSION  The prevalence of pulmonary arterial hypertension is high in patients with atrial fibrillation. Non-paroxysmal atrial fibrillation, right atrial enlargement and left ventricular ejection fraction are independent risk factors for atrial fibrillation associated with pulmonary arterial hypertension.

       

      • HTML全文
      • 参考文献(11)
      • 相关文章
      • 施引文献
    • 资源附件(0)

    /

    返回文章
    返回