AIM  To evaluate the safety and effectiveness of transcatheter closure of ruptured sinus of valsalva aneurysm.

  METHODS  Twenty-seven patients with ruptured sinus of valsalva aneurysm were collected from the Department of Cardiology, the Second Affiliated Hospital of the Air Force Medical University from April 2013 to July 2020. The position of the occluder, residual leakage, complications and other information of the patients after interventional therapy were collected and observed, and the patients’ cardiac functions, cardiac murmur, heart rate, blood pressure, cardiac cavity size and other indicators before and after interventional therapy were compared.

  RESULTS  Echocardiography showed that 27 patients received successful closure, 24 patients had no residual leakage and 3 patients had minimal residual leakage. No serious complications occurred. One case had fever and 1 case had decreased platelet, which were cured or alleviated before discharge. Postoperative cardiac functions were significantly improved after interventional therapy. Auscultation murmurs disappeared in 26 patients and 1 patient had grade 3/6 systolic murmurs in the 3rd intercostal margin of the left sternum. Heart rate after operation was significantly lower than that before operation (P<0.05). There was no significant difference in blood pressure before and after operation. Echocardiography at 72nh after surgery showed that the diameter of the right atrial was reduced compared with that before interventional therapy (P<0.05). Echocardiography one year after operation showed that the diameters of the right chamber, right ventricle, left atrium, and the systolic and diastolic diameter of the left ventricle were decreased compared with those before surgery (P<0.05).

  CONCLUSION  Transcatheter closure is a safe and effective method for ruptured sinus of valsalva aneurysm in patients with suitable indications.