Abstract:
AIM To investigate the safety and efficacy of drug coated balloon (DCB) in patients with acute ST-segment elevation myocardial infarction (STEMI) during percutaneous coronary intervention (PCI).
METHODS Eighty STEMI patients in our department from September 2018 to December 2018 were enrolled and divided into DCB group (n=38) and drug-eluting stents group (DES). The patients were followed up for one year and their chocardiography and major adverse cardiac events (MACEs) were collected at 1 month, 6 months and 1 year after operation. Late lumen loss (LLL) was examined during coronary angiography at 1 year after operation.
RESULTS At the follow-up of 6 months and 1 year after operation, the left ventricular ejection fraction (LVEF) and the left ventricular end diastolic diameter (LVEDD) in two groups were all improved compared with those during hospitalization. The difference was statistically significant (P<0.05) and there was no statistically significant difference between the two groups. The LLL in DCB group was (−0.12±0.46) mm and that in DES group was (0.14±0.37) mm, with statistically significant difference (P<0.05). The incidence of MACEs was 10.5% in DCB group and 11.9% in DES group, with no statistically significant difference between the two groups.
CONCLUSION DCB treatment is safe and effective in patients with STEMI during PCI and one-year follow-up shows good clinical and angiographic results.
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