Abstract: The development of information-based teaching provides an opportunity for the reform of aerospace medicine teaching system and further improves aerospace cardiovascular educational content. Chaoxing Learning APP is a mobile platform of knowledge. Based on the unique advantage of the platform, Problem-based Learning (PBL), Flipped Class Model and Microlectures are combined with the learning platform, and aerospace cardiovascular educational resources are made full use of. In building the knowledge system for students, the instructors also help students to establish basic learning methods such as autonomous learning and cooperative learning and pay more attention to thinking model and personal qualities. Chaoxing Learning APP is applied in aerospace cardiovascular courses, which improves the teaching effect.