Abstract:
AIM To study the evaluation value of echocardiographic coronary layer- and segmental- specific strain in the myocardial ischemia/reperfusion injury (MI/RI) after percutaneous coronary intervention (PCI).
METHODS Forty-eight patients who underwent emergency primary PCI were included, among whom 25 patients demonstrated clinical MI/RI, while the other 23 did not. Two-dimensional speckle tracking echocardiography was performed before and after PCI for evaluation of layer-specific global longitudinal strain (GLS). Segmental longitudinal strain (SLS) was also analyzed based on the territorial distribution of intervened coronary arteries. The baseline strains and percentage changes of strain after PCI were compared between control group and MI/RI group and the ROC curve was used to determine the prognostic value of baseline SLS for MI/RI after PCI.
RESULTS Compared with those in control group, all baseline layer-specific SLS decreased in MI/RI patients. After PCI, GLS and SLS of all layers in control group showed improvement, while those in MI/RI group showed the opposite. The baseline endocardial coronary SLS could predict MI/RI after PCI and the areas under ROC curve was 0.86 (P<0.01), with a sensitivity of 0.85 and a specificity of 0.88.
CONCLUSION The echocardiographic coronary layer- and segmental- specific strain could be used to evaluate MI/RI after PCI and the baseline SLS could effectively predict MI/RI after PCI.
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