Abstract: Pulmonary artery hypertension (PAH) is a common syndrome that can be induced by stronger vascular resistance and increased blood flow. Hypoxic pulmonary hypertension (HPH) is a syndrome characterized by hypoxia-induced pulmonary artery resistance and hypoxia-induced pulmonary vascular remodeling. Both acute and chronic hypoxia can cause interleukin-6 secretion, which induces PAH through endarterial remodeling.