Abstract: AIM: To compare the clinical effectiveness of Chinese-made occluders and surgical procedures in closure of patent ductus arteriosus (PDA). METHODS: Major complications and long-term clinical results of PDA closure were compared among 79 patients treated with Chinese-made occluders and 33 patients treated surgically. RESULTS: In the group treated with Chinese-made occluders, the technical success rate was 99%. Hemoglobinuria occurred in one case (1%). The one unsuccessful case underwent surgical closure. All patients in the surgical group were successfully treated. Pulmonary atelectasis occurred in one case, hydrothorax in two cases, progressive hemothorax in one case and incision infection in one case. The major complication rate was 15%. Long-term follow-up demonstrated postoperative recanalization in one case, rib osteomylitis in one case, and chest pain in one case. CONCLUSION: Chinese-made occludes are safe and reliable in transcatheter closure of PDA, with fewer complications and better long-term results than surgical procedures.