老年原发性高血压患者晨峰现象与左心室肥厚

Association between morning blood pressure surge and left ventricular hypertrophy in elderly patients with essential hypertension

摘要: 目的: 探讨老年原发性高血压晨峰现象与左心室肥厚的关系。方法: 老年原发性高血压患者107例根据24 h动态血压监测分为有晨峰现象（MBPS）组（40例）和无晨峰现象（NMBPS）组（67例），检查空腹血脂、血糖和肌酐，并计算体质量指数（BMI）和左室质量指数（LVMI）。结果: MBPS组的24 h动态血压监测收缩压高于NMBPS组（P<0.05）。MBPS组的LVMI显著高于NMBPS组［（132±28）g/m2 vs.(113±28)g/m2，P<0.01］。结论: 老年原发性高血压有晨峰现象者更易发生左心室肥厚。

Abstract: AIM: To explore the association between morning blood pressure surge (MBPS) and left ventricular hypertrophy in elderly patients with essential hypertension. METHODS: One hundred and seven patients under 24 h ambulatory blood pressure monitoring were categorized as with MBPS (n=40) and no MBPS (NMBPS) (n=67) and their total cholesterol, body mass index (BMI) and left ventricular mass index (LVMI) were determined. RESULTS: Systolic blood pressure in MBPS was higher than in NMBPS (P<0.05). LVMI in MBPS was higher than in NMBPS ［(132± 28) g/m2 vs.(113±28) g/m2, P<0.01］. CONCLUSION: Morning blood pressure surge is closely related with the development of left ventricular hypertrophy in elderly patients with essential hypertension.