Abstract: Noise is one of the most significant environmental problems. Prolonged exposure to noise can not only damage the auditory organs, leading to noise-induced hearing loss, but can also cause significant non-auditory damage, especially inducing hypertension. Epidemiologic data suggest a possible interaction between hypertension and hearing loss. Hypertension can affect the auditory system alone causing hearing loss, or it can exacerbate the degree of noise-induced hearing loss, while noise-induced cochlear pathology has the potential to induce or exacerbate the onset of hypertension. In this paper, we review the research progress on the interaction mechanism between hypertension and hearing loss to provide theoretical references for further research on noise protection and cardiovascular disease prevention and treatment.