半乳糖凝胶素-3在心肾综合征中的研究进展

Research progress of galactogelin-3 in cardiorenal syndrome

摘要: 心肾综合征（cardiorenal syndrome，CRS）是一种由于心脏或肾脏中的一个器官出现急性或慢性功能不全从而导致另一器官同样出现急性或慢性功能紊乱的一种病理状态。虽然目前对CRS诊断及治疗的认识越来越多，但并没有特异的生物标志物用于对CRS的早期诊断及治疗靶点。近年来，大量研究表明半乳糖凝胶素-3（galectin-3，Gal-3）可作为心脏和肾脏疾病中新型的生物标志物，为 CRS 诊治提供新思路。

Abstract: Cardiorenal syndrome (CRS) is a condition in which acute or chronic dysfunction of one organ of the heart or kidney results in acute or chronic dysfunction of the other organ. Although the diagnosis and treatment of CRS are increasingly understood, there are no specific biomarkers for the early diagnosis and treatment of CRS. In recent years, a large number of studies have shown that Galectin-3 (Gal-3) can be used as a novel biomarker in heart and kidney diseases,to provide a new way of diagnosis and treatment of CRS.