薛文静, 杨一格, 柴若宁, 石树青, 石晶晶, 张雪松, 胡元会. Rho/ROCK信号通路与炎症细胞因子的研究进展[J]. 心脏杂志, 2023, 35(1): 94-98. DOI: 10.12125/j.chj.202108066
    引用本文: 薛文静, 杨一格, 柴若宁, 石树青, 石晶晶, 张雪松, 胡元会. Rho/ROCK信号通路与炎症细胞因子的研究进展[J]. 心脏杂志, 2023, 35(1): 94-98. DOI: 10.12125/j.chj.202108066
    Wen-jing XUE, Yi-ge YANG, Ruo-ning CHAI, Shu-qing SHI, Jing-jing SHI, Xue-song ZHANG, Yuan-hui HU. Research progress of Rho/ROCK signaling pathway and inflammatory cytokines[J]. Chinese Heart Journal, 2023, 35(1): 94-98. DOI: 10.12125/j.chj.202108066
    Citation: Wen-jing XUE, Yi-ge YANG, Ruo-ning CHAI, Shu-qing SHI, Jing-jing SHI, Xue-song ZHANG, Yuan-hui HU. Research progress of Rho/ROCK signaling pathway and inflammatory cytokines[J]. Chinese Heart Journal, 2023, 35(1): 94-98. DOI: 10.12125/j.chj.202108066

    Rho/ROCK信号通路与炎症细胞因子的研究进展

    Research progress of Rho/ROCK signaling pathway and inflammatory cytokines

    • 摘要: Rho/ROCK通路与细胞的生长、发育、分化以及迁移密切相关。大量研究表明Rho/ROCK途径与炎症细胞因子的相互作用对糖尿病、眼炎症性疾病、肿瘤、肺损伤、心脏病和神经损伤性疾病的发生发展产生了一定的影响,以该通路作为疾病的治疗靶点越来越得到人们的广泛关注,通过总结近年来Rho/ROCK信号通路与炎症细胞因子的相关研究,为中药降压、抗动脉粥样硬化的进一步研究提供参考。

       

      Abstract: The Rho/ROCK pathway is closely related to cell growth, development, differentiation and migration. A large number of studies have shown that the interaction of the Rho/ROCK pathway and inflammatory cytokines has a certain impact on the occurrence and development of diabetes, ocular inflammatory diseases, tumors, lung injury, heart disease, and nerve injury diseases. This pathway is used as a therapeutic target for diseases and receives more and more attention. By summarizing the research on Rho/ROCK signaling pathway and inflammatory cytokines in recent years, we hope to provide reference for the further research of Chinese medicine in lowering blood pressure and resisting atherosclerosis.

       

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