纪佳伯, 张磊, 马浩诚, 易甫. 持续性房颤非药物治疗现状[J]. 心脏杂志, 2019, 30(1): 107-110. DOI: 10.12125/j.chj.201801022
    引用本文: 纪佳伯, 张磊, 马浩诚, 易甫. 持续性房颤非药物治疗现状[J]. 心脏杂志, 2019, 30(1): 107-110. DOI: 10.12125/j.chj.201801022
    Jia-bo JI, Lei ZHANG, Hao-cheng MA, Fu YI. Current strategies of non-pharmacological therapy for persistent atrial fibrillation[J]. Chinese Heart Journal, 2019, 30(1): 107-110. DOI: 10.12125/j.chj.201801022
    Citation: Jia-bo JI, Lei ZHANG, Hao-cheng MA, Fu YI. Current strategies of non-pharmacological therapy for persistent atrial fibrillation[J]. Chinese Heart Journal, 2019, 30(1): 107-110. DOI: 10.12125/j.chj.201801022

    持续性房颤非药物治疗现状

    Current strategies of non-pharmacological therapy for persistent atrial fibrillation

    • 摘要: 持续性房颤(AF)为最常见的持续性心律失常,会使患者死亡率及卒中风险增加,生活质量以及运动耐力下降。随着各种AF发病机制假说的提出以及人体工程学的不断进步,人们找到了不同的非药物治疗方式,如通过介入的方法进行肺静脉隔离及肺静脉外的额外线性消融,但维持窦性心律的效果较差,外科maze手术可以使维持窦性心律的效果明显增加,但手术创伤大、操作复杂且并发症增加,使其在临床推广上受到限制。目前,内外科结合治疗持续性AF的杂交手术在一些临床试验中取得良好的疗效,本文将近年持续性AF非药物治疗的进展进行了综述。

       

      Abstract: Persistent atrial fibrillation (AF) is the most common sustained arrhythmia and is associated with increased risk of mortality, stroke, and decreased quality of life and sports endurance. With progress in AF pathogenesis understanding and human engineering techniques, different non-pharmacological therapies, such as interventional pulmonary vein isolation and extra linear ablation beyond the pulmonary vein are taken but results have been inadequate in maintaining sinus rhythm. The higher risk of surgical trauma, complexity in operation and post-operation complications restrict clinical promotion of surgical treatment. Several studies have shown some improvements in patients with persistent AF undergoing hybrid surgical and catheter ablation. This investigation summarizes recent progress in non-pharmacological therapy for persistent atrial fibrillation.

       

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