Genetic polymorphism analysis of CYP2C19 in Shaanxi Han population after percutaneous coronary intervention

AIM To study the characteristics of CYP2C19 genotype in Shaanxi Han population after percutaneous coronary intervention (PCI) and establish a foundation for individualized treatment. METHODSGenotyping of CYP2C19 in 1 220 Shaanxi Han patients after PCI were determined by gene chip. RESULTSAccording to genotyping results, the frequencies of wild type (WT) *1*1 in Shaanxi Han population were 34.02%, WT *1*2 and *1*3 were 33.61%, and WT *2*2, *2*3 and *3*3 were 9.43% in males. The frequencies of WT *1*1 were 9.34%, WT *1*2 and *1*3 were 11.23%, and WT *2*2, *2*3 and *3*3 were 2.38% in females. CONCLUSIONGenetic polymorphism analysis of CYP2C19 WT *1*1 and *1*2 in Shaanxi Han population after PCI are most frequent.