The clinical study of coronary artery lesion characteristic, clinical feature and risk factor in Uygur and Han elderly patients with acute coronary syndrome

AIM To investigate the characteristics of coronary artery lesion, clinical feature in elderly patients with acute coronary syndromes (ACS) of Uygur and Han nationality, and risk factors of Uygur elderly patients with coronary artery C type lesions. METHODS Retrospective analysis of 330 hospitalized patients with a diagnosis of ACS combined with coronary angiography ages≥65 years old; Uygur and Han patients basic data, Lipoprotein a (Lpa), Serum uric acid (UA), Cystatin C (CysC), Retinol binding protein 4 (RBP4), Fibrinogen (FG) and other biochemical indicators. According to the results of coronary angiography coronary artery lesions characterized by coronary artery superiority classification, pathological vascular count, vascular lesions, vascular disease classification, and Gensini points. The subjects were divided into Uygur elderly ACS group (154 cases) and Han elderly ACS group (176 cases). According to the results of coronary angiography in elderly patients with ACS were divided into Uygur elderly patients with ACS type C coronary disease group (99 cases) and Uygur elderly patients with ACS non type C lesion group (55 cases), analyze the risk factors of Uygur with coronary artery C type lesion. RESULTS The coronary artery C type lesion and Gensini score in the Uygur group were significantly higher than that in the Han nationality group (P<0.05). The risk factors of coronary artery C type lesions in Uygur elderly patients with ACS were Hypertension (OR=4.324), Hyperlipidemia (OR=3.732), Fibrinogen (OR=1.827), Uric acid (OR=1.006), Lipoprotein a (OR=1.003), P<0.05. CONCLUSION There were national differences in risk factors among Uygur and Han elderly patients with ACS. The incidence rate of C type lesions in Uygur elderly acute coronary syndrome patients is higher and the degree of coronary lesions were more serious than that of the older Han patients. Hypertension, Hyperlipidemia, Fibrinogen, Lipoprotein a and Uric acid are risk factors for the coronary artery C type lesion in Uygur elderly patients with ACS.