Clinical advances in research of fully bioresorbable scaffolds

Percutaneous coronary intervention (PCI) has become the major method to treat coronary artery diseases (CAD). Second-generation drug-eluting stents (DES) have significantly reduced the occurrence of in-stent restenosis (ISR) and target lesion revascularization (TLR) compared with bare metal stents. However, DES cannot fundamentally resolve the problem caused by permanent mental stents. Fully bioresorbable scaffolds (BRS) are designed to provide temporary support to the vessel walls and subsequently dissolve. BRS have become the focus of current cardiovascular intervention due to the theoretical advantages of the new technology. This article will review the main types of BRS, relevant clinical research and limitations.