Clinical implication of precordial ST segment depression in patients with acute inferior myocardial infarction

AIM: To investigate the relationship between coronary lesion characteristics and precordial ST segment depression and its clinical implication in patients with acute inferior myocardial infarction (AIMI). METHODS: Ninety one patients with the first AIMI were divided into four groups on the basis of admission electrocardiograms: Group I—patients with no precordial ST segment depression (n=27), Group II—patients with ST segment depression in leads V1 to V4 (n=26), Group III—patients with ST segment depression in leads V5-V6 (n=12) and Group IV of patients with ST segment depression in leads V1-V6 (n=26). RESULTS: V1-V4 ST segment depression in AIMI was negatively correlated with multivessel lesion (ORIII=0.38, P>0.05), whereas V1-V6 ST segment depression in AIMI was positively correlated with multivessel lesion (ORIV=5.25, P<0.01) and lower left ventricular ejection fraction (P<0.01). CONCLUSION: V1-V6 ST segment depression in AIMI suggests higher incidence of multivessel lesion and heart failure.