Progress in energy metabolism regulation of cardiomyocytes

Research on the release, transport, storage, and use of energy in the process of metabolism has been conducted for hundreds of years. The heart is relatively active among the energy metabolism organs and studies have shown that the daily conversion quantity of heart ATP is 15-20 times of its weight. Diabetic cardiomyopathy, ischemic cardiomyopathy, hypertrophic cardiomyopathy, dilated cardiomyopathy, and many other diseases are closely related to myocardial cell energy metabolism disorders. Research on myocardial cell energy metabolism and its regulation mechanism is of important guiding significance for the treatment of these diseases. In recent years, many scholars have conducted in-depth studies in this regard and this article summarizes findings from the choice of substrate, sugar metabolism, and lipid metabolism.