Types of angina pectoris are associated with stress-induced hypertension and inflammatory factors

AIM:To investigate the relationship of the types of angina pectoris, stress-induced hypertension and inflammatory factors. METHODS: Eight hundred patients with angina diagnosed by coronary angiography were divided into two groups: stable angina pectoris (SAP) group (200 cases) and unstable angina pectoris (UAP) group (600 cases). The levels of serum IL-6, IL-8 and high-sensitivity C-reactive protein (hs-CRP) were measured using ELISA. Blood pressure was monitored during coronary angiography and patients with stress-induced hypertension were grouped according to blood pressure ≥140/90 mmHg during coronary angiography and with normal blood pressure before the procedure. Meanwhile, independent factors that influnced the types of angina pectoris were analyzed by binary logistic regression. RESULTS: During coronary angiography, stress-induced hypertension was mainly detected in patients with UAP, whereas non-stress-induced hypertension was mainly shown in patients with SAP. The levels of serum IL-6, IL-8 and hs-CRP of patients with UAP were markedly higher than those of patients with SAP (P<0.05). A group of independent factors including stress-induced hypertension, IL-6, IL-8 and hs-CRP were demonstrated to significantly influence the type of angina pectoris by logistic regression analysis. CONCLUSION: Type of angina pectoris was determined to be associated with stress-induced hypertension as well as inflammatory factors.