Effect of blood sugar levels on clinical treatment and prognosis in coronary heart disease patients with diabetes

AIM To examine the effect of blood sugar levels on clinical treatment and prognosis in coronary heart disease (CHD) patients with diabetes. METHODSOne hundred and twenty CHD patients from January 2013 to January 2015 in our hospital were selected and divided into CHD without diabetes mellitus group (group A, n=30, fasting glucose<7.0 tendency/L), CHD with diabetes and low blood sugar group (group B, n=50, 8.0 mmol/L>fasting glucose≥7.0 mmol/L), and CHD with diabetes and hyperglycemia group (group C, n=40, fasting glucose 8.0 mmol/L). Blood pressures and biochemical indicators, including serum total cholesterol, low density lipoprotein, apolipoprotein, fibrinogen, triglyceride, uric acid, and the incidence of the complications of acute myocardial infarction were measured and analyzed. RESULTSAverage systolic blood pressure in group A and group B was (138.9±20.3) mmHg and (139.2±21.0) mmHg, and diastolic blood pressure was (82.6±10.5) mmHg and (83.1±11.3) mmHg, with no significant difference (P>0.05). Serum total cholesterol, low density lipoprotein, apolipoprotein levels and left ventricular end-diastolic diameter in group C were significantly higher than those in group B, and these parameters in group B were significantly than those in group A (P<0.05). No statistical difference was observed in triglycerides, fibrinogen and uric acid levels among the three groups. Postoperative acute myocardial infarction, acute myocardial infarction with malignant arrhythmia, incidence of acute myocardial infarction with heart failure and death rate in group A were lower than those in group B and group C (P<0.05), and these rates in group C were higher than those in group B (P<0.05). CONCLUSIONBlood glucose levels in diabetic patients have some influence on biochemical indicators and complications. Good control of blood sugar level has a positive effect on the treatment and prognosis in CHD patients with diabetes mellitus.