DNA methylation and cardiovascular disease
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Graphical Abstract
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Abstract
DNA methylation is a pervasive feature of eukaryotic genomes, which is fundamental for cellular differentiation processes and control of transcriptional potentials. DNA methylation patterns can be inherited and influenced by the environment, diet and aging and can be disrupted in diseases. Recent evidence has suggested that DNA methylomes is important in the development of cardiovascular diseases including atherosclerosis, hypertension and heart failure.
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