Prognostic value of statins on 1-year major adverse cardiac events in ST-elevated myocardial infarction after percutaneous coronary intervention

AIM To investigate the relationship between long-term statin pretreatment and 1-year major adverse cardiac events in patients with ST-elevated myocardial infarction (STEMI) after percutaneous coronary intervention (PCI). METHODS Three hundred and one STEMI patients were divided into group A (no long-term statin pretreatment, n=198) and group B (long-term statin pretreatment, n=103). Patients were followed-up for 1 year and clinical data and cardiovascular and cerebrovascular events (MACCE) were analyzed. The independent effect of variables on the prognosis was calculated using binary logistic regression analysis. RESULTS MACCE rate was higher in group A than in group B (P<0.05). This difference resulted from recurrent angina (P<0.01) and rehospitalization (P<0.01). In binary logistic regression analysis, long-term statin pretreatment was a protective factor in STEMI patients after PCI (OR 0.24, 95%CI 0.10-0.55, P<0.01). CONCLUSION Long-term statin pretreatment can reduce 1-year MACCE rate in STEMI patients after PCI and is a protective factor.