Correlation of renal resistive index and high-sensitive C-reactive protein in patients with essential hypertension

AIM:To explore the correlation of renal resistive index (RRI) and high-sensitive C-reactive protein (hsCRP) in patients with essential hypertension. METHODS: Eighty-two patients with primary hypertension were selected and RRI was detected in all cases by color Doppler flow imaging. The patients were divided into group A (RRI≥0.7, n=34) and group B (RRI<0.7, n=48) according to RRI, systolic blood pressure (SBP) and diastolic blood pressure (DBP) measured on the same day of the examination. Pulse pressure (PP) and mean blood pressure (MBP) were calculated. Blood urea nitrogen (BUN) and serum creatinine (Scr) were measured. hsCRP was measured with immunoturbidimetric assay. All results were compared between groups. RESULTS: Age, PP, SBP and hsCRP levels in group A were obviously higher than those in group B (P<0.01). Linear correlation analysis showed that RRI and hsCRP were positively correlated. CONCLUSIONS: RRI is related to early renal hemodynamic changes. Higher levels of hsCRP may be one reason for the intrarenal hemodynamic changes in primary hypertension patients with early renal damage.