Predictors of positive inotropic drug use in patients undergoing concomitant coronary artery bypass graft without cardiopulmonary bypass

AIM:To identify the demographic, clinical, laboratory, echocardiographic and hemodynamic factors that are associated with the use of inotropic drugs in patients undergoing concomitant coronary artery bypass graft without cardiopulmonary bypass. METHODS: The study included 630 patients ［male 351, female 279; average age (68.6±9.7) years］ who underwent concomitant coronary artery bypass graft at our hospital from January 2012 to December 2013. Positive inotropic drug support was given in 330 patients and was not given in 300 patients. All data were collected retrospectively after reviewing original medical records. Inotropic support was defined as the use of dopamine≥5 μg/(kg·min), any dose of epinephrine or norepinephrine and milrinone at the separation from cardiopulmonary bypass. RESULTS: The study identified three significant and independent predictors of inotrope use: cardiac index 2.5 L/(min·m2), LVEF 35% and LVEDP≥25 mmHg. CONCLUSION: Cardiac index 2.5 L/(min·m2), LVEF 35% and LVEDP≥25 mmHg are independent predictors of inotropen use.