Neutrophilic granulocyte percentage is associated with depression in patients with chronic heart failure

AIM To observe and analyze the association between neutrophilic granulocyte percentage and depression in patients with chronic heart failure. METHODS The study population consisted of patients with chronic heart failure. The enrolled patients received Hamilton Depression Scale (HAMD) for depression evaluation. The blood test results were documented.Patients were classified into groups based on HAM-D score, according to whether have depression divided into depression group (n=105) and nodepression group (n=78). The significantly correlated factors were enrolled in Logistic regression for adjustment. RESULTS Single factor analysis showed that there was significant difference between two groups in gender difference, NYHA classification, neutrophils granulocyte percentage, total cholesterol, low density lipoprotein cholestero and serum creatinine. Logistic regression analysis showed that gender difference, NYHA classification, neutrophils granulocyte percentage, total cholesterol, was still a significant risk factor of depression in patients with chronic heart failure patients with chronic heart failure (OR=1.043, P=0.000). CONCLUSION The neutrophils granulocyte percentage was significantly increaseed in chronic heart failure patients with depression symptoms.