Relationship between uric acid and prognosis in patients with severe congestive heart failure

AIM To investigate the association between serum uric acid(SUA) and prognosis in patients with severe congestive heart failure(CHF). METHODS One hundred and eighty-nine consecutive patients with severe CHF hospitalized from April 2014 to January 2015 were included and the incidence of all-cause mortality during 6 months was observed. Statistical analyses were performed using SPSS 17.0. RESULTS Compared with the control group, uric acid level was significantly increased in all-cause mortality group(514±30) vs.(432±32) μmol/L, P<0.01. Pearson related analysis indicated that the uric acid level was positively related to NT-proBNP(r=0.345, P<0.05). Multiple logistic regression analysis found that uric acid levels(OR=1.213, 95%CI:1.081-3.621, P<0.05), NT-proBNP(OR=1.456, 95%CI:1.113-5.432, P<0.01) and diabetes(OR=2.105, 95%CI:1.221-4.553, P<0.05) were the independent risk factors for all-cause mortality within 6 months in severe CHF patients. CONCLUSION SUA level is associated with the prognosis in patients with severe CHF.