Research progress of myocardial energy metabolism remodeling in cardiac hypertrophy
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Graphical Abstract
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Abstract
The heart needs to use a lot of energy to maintain systolic function, so energy metabolism is crucial for the heart function. The remodeling of cardiac energy metabolism is mostly considered from the perspective of energy supply. However, the results of myocardial energy metabolism remodeling in cardiac hypertrophy are not limited to impaired energy supply, and the influence of intermediate products on cardiac function is equally important. The study from the perspective of energy metabolism may explore some new targets for the prevention and treatment of cardiac hypertrophy. In this paper, the changes of myocardial energy metabolism during cardiac hypertrophy were summarized and the recent studies on the effects of energy metabolism intermediates on the cardiac function were reviewed.
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