ZHANG Li-wen, HE Gui-xin, OUYANG Shun-bin, LIU Shan-ping, ZHAN Ling-jun, SONG Hui, QIN Wei-bin. Role of the orphan nuclear receptor NR4A1 in atherosclerosis and myocardial infarction[J]. Chinese Heart Journal, 2025, 37(2): 210-215. DOI: 10.12125/j.chj.202305057
    Citation: ZHANG Li-wen, HE Gui-xin, OUYANG Shun-bin, LIU Shan-ping, ZHAN Ling-jun, SONG Hui, QIN Wei-bin. Role of the orphan nuclear receptor NR4A1 in atherosclerosis and myocardial infarction[J]. Chinese Heart Journal, 2025, 37(2): 210-215. DOI: 10.12125/j.chj.202305057

    Role of the orphan nuclear receptor NR4A1 in atherosclerosis and myocardial infarction

    • In recent years, the orphan nuclear receptor NR4A1 has become a hot topic in the cardiovascular field. Its expression is influenced by a variety of external stimuli and can be widely distributed in a variety of tissues and cells, and it can also participate in the regulation of cell differentiation, proliferation, survival and apoptosis, and its function is also considered to have a critical impact on the inflammatory response and vascular remodeling. In this paper, we review the role of NR4A1 receptors in atherosclerosis and myocardial infarction.
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