Effect of alcohol consumption on the risk of atrial block in people with different blood pressure

  AIM  To explore the effect of drinking on the risk of intra atrial block (IAB) in people with different blood pressure, so as to provide a strong basis for the prevention and treatment of IAB caused by drinking in people with different blood pressure.

  METHODS   In order to assess the risk of IAB in people with different blood pressure and alcohol intake, 11271 permanent residents of the rural cardiovascular and cerebrovascular health research cohort in Northeast China over the age of 35 were divided into non IAB group (n=10559) and IAB group (n=712) according to whether IAB occurred (P wave width ≥0.12 s). The stratified study was divided into four groups: non drinking normal blood pressure group (n=4321), non drinking hypertension group (n=4178), drinking normal blood pressure group (n=1201) and drinking hypertension group (n=1571). Baseline structure analysis, stratified analysis and multivariate logistic regression analysis were carried out.

  RESULTS   After adjusting for confounding factors, the prevalence of IAB in patients with hypertension combined with drinking was significantly higher than that in non hypertensive population. OR value was 1.47 ,the 95% confidence interval was (1.04～2.07) , which was statistically significant (P<0.01). In normal blood pressure population, drinking or not was not an important factor affecting the prevalence of IAB, Drinking or not is an important influencing factor of IAB in hypertensive population. Hypertension is an important risk factor of IAB, whether in drinking population or non drinking population.In patients with IAB, the risk of IAB caused by grade II and III blood pressure is much higher than that of normal blood pressure and grade I hypertension. For the drinking grade II blood pressure group (160/100mmHg≤BP<180/110 mmHg) , OR(95% CI) was 1.64 (1.08～2.50); for drinking grade III blood pressure group (BP≥180/110 mmHg) ,OR(95% CI) was 1.73 (1.03～2.89), both of which were statistically significant. In the grade I hypertension (140/90mmHg ≤ BP < 160/100 mmHg) in patients with drinking , OR(95% CI) was 1.32 (0.90～1.92), intra atrial block has no obvious correlation with blood pressure, and there was no significant correlation between blood pressure and alcohol consumption in non-drinkers.

  CONCLUSION   The effect of alcohol consumption on the risk of intra atrial block (IAB) was significantly different in different blood pressure groups