Long-term quality of life in acute coronary syndrome patients after first percutaneous coronary intervention and its influencing factors

  AIM   To identify factors influencing the long-term (>1 year) quality of life (QoL) after first percutaneous coronary intervention (PCI) in patients with acute coronary syndrome (ACS).

  METHODS  A sample of 451 consecutive ACS patients over 1 year after their first PCI was included. The Seattle angina questionnaire (SAQ) was completed and the baseline and review data were collected. The scores of each dimension and summary score of SAQ were calculated, the influencing factors were sorted out by multivariate analysis and the prediction model was established by linear regression.

  RESULTS  More than 1 year after the first PCI, the scores of SAQ physical limitation, angina stability, angina frequency, treatment satisfaction and disease perception were 70.190 ± 16.972, 42.180 ± 19.109, 82.680 ± 21.790, 88.561 ± 10.448 and 70.972 ± 23.670 respectively, and the summary score was 74.615 ± 15.551. Linear regression showed that the factors affecting scores on more than three dimensions were: current type of coronary artery disease, male, angina symptom onset, baseline leukocyte count, and baseline glycosylated hemoglobin.

  CONCLUSION  Current type of coronary heart disease, male, angina symptom onset, baseline leukocyte count, and baseline glycosylated hemoglobin are the main influencing factors of long-term QoL after the first PCI in ACS patients. These findings may help clinicians to prospectively understand which patients are most likely to benefit from the long term after first PCI, so as to improve the long-term QoL of patients as much as possible.