AIM To study the safety and effect of interventional treatment for children with ventricular septal defect (VSD) combined with other cardiac malformations.
METHODS Retrospective analysis of patients’ clinical data from January 2016 to December 2020 in our center was performed. The enrolled patients included VSD combined with other congenital heart disease (CHD) receiving interventional therapy for multiple malformation and complex CHD postoperative residual shunt with VSD occlusion.
RESULTS There were 62 cases of VSD combined with other CHD, including 37 cases of atrial septal defect (ASD) and 25 cases of patent ductus arteriosus (PDA). Twenty-one were males and 41 females, with a median age of 36 m (23, 180) and median weight of 15 kg (11, 48). There were 11 complex CHD with residual VSD shunt post-operation. The shortest post-surgery time was 14 days, median post-surgery time was 56 months and median weight was 18.2 kg (11, 50). All cases received VSD interventional therapy. There was 1 case of multiple apical muscular VSD with occlude released through artery retrogradely and 1 case of muscular VSD completed through internal jugular vein pathway. Only 2 cases were found with little residual shunt after intervention and no atrioventricular block or significant aggravated atrioventricular or aortic regurgitation occurred after operation.
CONCLUSION Interventional therapy for children with VSD combined with other cardiac malformations is safe and effective. The specific methods and procedures need to be individualized according to different patients.
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