Application and analysis of cutting balloon combined with drug-coated balloon in de novo coronary artery lesions

  AIM  To evaluate the effect of cutting balloon combined with drug-coated balloon in the treatment of de novo coronary artery.

  METHODS  From August 11, 2017 to June 11, 2020, Ninety-one patients with de novo coronary artery were observed. According to different predilation methods, 37 patients predilated with cutting balloon were selected as the observation group and 54 patients predilated with non-compliant or semi-compliant balloon were selected as the control group. The successful rate of predilation in the two groups was compared. After 6 months of follow-up and coronary angiography examination, the incidence of target lesion restenosis and major cardiovascular adverse events in the two groups were compared.

  RESULTS  Thirty-six of the 37 patients were predilated successfully in the observation group and 40 of the 54 patients were predilated successfully in the control group, and there was statistical significance in the success rate of predilation between the two groups (P<0.05). Thirty-two of the 37 patients in the observation group and 38 of the 54 patients in the control group received drug-coated balloon only. The 6-month follow-up found 0 cases of restenosis of original target lesion and 1 case of revascularization of non-original target lesion in the observation group, and 3 cases with restenosis of original target lesion and 2 cases with revascularization of non-original target lesion in the control group, with no significant difference between the two groups.

  CONCLUSION  Cutting balloon is a feasible method as predilation in de novo coronary artery lesion. Combined with drug coated balloon, the target vessel failure rate is extremely low and the follow-up effect is good.