AIM To analyze the prevalence of pulmonary arterial hypertension (PAH) in patients with atrial fibrillation (AF) and the risk factors and the clinical characteristics of atrial fibrillation with pulmonary arterial hypertension.
METHODS A total of 292 patients with AF from November 2016 to November 2019 were recruited in this study. The patients were divided into two groups: paroxysmal AF group (n = 167) and non-paroxysmal AF group (n = 125). With echocardiography as the main diagnostic criteria, pulmonary hypertension was diagnosed by tricuspid regurgitation. Clinical data of the patients were collected for statistical analysis.
RESULTS Among the 292 patients, PAH was found in 100 patients (59.9%) in paroxysmal AF group and in 111 patients (88.9%) in non-paroxysmal AF group. Univariate analysis and multivariate logistic regression analysis showed that non-paroxysmal atrial fibrillation (P<0.05), right atrial enlargement (OR = 6.641, 95%CI 2.397~18.402, P<0.01) and left ventricular ejection fraction (P<0.01) were independent risk factors for atrial fibrillation with pulmonary arterial hypertension.
CONCLUSION The prevalence of pulmonary arterial hypertension is high in patients with atrial fibrillation. Non-paroxysmal atrial fibrillation, right atrial enlargement and left ventricular ejection fraction are independent risk factors for atrial fibrillation associated with pulmonary arterial hypertension.
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